NANOCARRIER PHOTODYNAMIC THERAPY

2010, Thienot E. et al.

Authors

Virginie Simon1, Kelthoum Piejos1, Audrey Darmon1, Jean-Francois Hochepied2, Edouard Thiénot1, Matthieu Germain1, Agnès Pottier1, Elsa Borghi1, Laurent Levy1 and Julie Marill*1
1 – Nanobiotix SA, rue de Wattignies, Paris, France
2 – Mines ParisTech, CEP/SCPI, 60, boulevard Saint-Michel, 75006 Paris, France

Summary

A new versatile hybrid nano carrier has been designed using a “soft chemistry” synthesis, to efficiently encapsulate a photosensitizer – the protoporphyrin IX (Pp IX) – while preserving its activity intact in biological environment for advantageous use in photodynamic therapy (PDT). […]