Thermosensitive | Nano Publications https://bibliography.nanobiotix.com/fr/ Navigate through all Nanobiotix publications online Thu, 05 May 2022 10:31:44 +0000 fr-FR hourly 1 https://wordpress.org/?v=6.0.1 https://bibliography.nanobiotix.com/wp-content/uploads/2019/11/cropped-n-icon-512x512-32x32.png Thermosensitive | Nano Publications https://bibliography.nanobiotix.com/fr/ 32 32 2011 – CLINAM Abstract – Thermosensitive Magnetoliposomes for MRI-Guided Drug Delivery – Meyr et al. https://bibliography.nanobiotix.com/fr/2011-clinam-abstract-thermosensitive-magnetoliposomes-for-mri-guided-drug-delivery-meyr-et-al/ https://bibliography.nanobiotix.com/fr/2011-clinam-abstract-thermosensitive-magnetoliposomes-for-mri-guided-drug-delivery-meyr-et-al/#respond Tue, 07 Feb 2017 17:06:16 +0000 http://bibliography.nanobiotix.com/2017/02/07/2011-clinam-abstract-thermosensitive-magnetoliposomes-for-mri-guided-drug-delivery-meyr-et-al-2/ Congress: CLINAM, 23rd May 2011 – The development of new activatable drug nanocarriers, with multiple functionalities, presents a promising approach for cancer treatment. Improved drug delivery and controlled drug release at the tumor site may have considerable benefit by increasing treatment efficacy while reducing side effects and toxicity. Further, the possibility to monitor both nanocarrier accumulation and drug release via current clinical imaging techniques may be particularly relevant for an optimal treatment.

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Authors

Marie-Edith Meyre1, Cyril Lorenzato2, Matthieu Germain1, Pierre Smirnov2, Chrit Moonen2, Agnès Pottier1 and Laurent Levy1
1 – Nanobiotix, Paris, France
2 – Laboratoire Imagerie Moléculaire et Fonctionnelle. UMR 5231 CNRS / Université Bordeaux 2. France

Summary

Congress: CLINAM, 23rd May 2011

Contents: The development of new activatable drug nanocarriers, with multiple functionalities, presents a promising approach for cancer treatment.

Improved drug delivery and controlled drug release at the tumor site may have considerable benefit by increasing treatment efficacy while reducing side effects and toxicity. Further, the possibility to monitor both nanocarrier accumulation and drug release via current clinical imaging techniques may be particularly relevant for an optimal treatment.

Within the European project “Sonodrugs”, we investigated the opportunity of triggering the drug release from new nanocarriers (temperature and pressure-sensitive) thanks to High Intensity Focused Ultrasounds (HIFU) and monitoring the release profile of the drug at the tumor site thanks to Magnetic Resonance Imaging (MRI) imaging.

A new versatile thermosensitive liposome has been designed and developed to efficiently encapsulate a drug (doxorubicin) and a contrast agent (superparamagnetic iron oxide nanoparticles).

The post 2011 – CLINAM Abstract – Thermosensitive Magnetoliposomes for MRI-Guided Drug Delivery – Meyr et al. first appeared on Nano Publications.]]> https://bibliography.nanobiotix.com/fr/2011-clinam-abstract-thermosensitive-magnetoliposomes-for-mri-guided-drug-delivery-meyr-et-al/feed/ 0 2011 – CLINAM Abstract – Thermosensitive Magnetoliposomes for MRI-Guided Drug Delivery – Meyr et al. https://bibliography.nanobiotix.com/fr/2011-clinam-abstract-thermosensitive-magnetoliposomes-for-mri-guided-drug-delivery-meyr-et-al/ https://bibliography.nanobiotix.com/fr/2011-clinam-abstract-thermosensitive-magnetoliposomes-for-mri-guided-drug-delivery-meyr-et-al/#respond Tue, 07 Feb 2017 17:06:16 +0000 http://localhost:8888/bibliography/2017/02/07/2011-clinam-abstract-thermosensitive-magnetoliposomes-for-mri-guided-drug-delivery-meyr-et-al/ Congress: CLINAM, 23rd May 2011 – The development of new activatable drug nanocarriers, with multiple functionalities, presents a promising approach for cancer treatment. Improved drug delivery and controlled drug release at the tumor site may have considerable benefit by increasing treatment efficacy while reducing side effects and toxicity. Further, the possibility to monitor both nanocarrier accumulation and drug release via current clinical imaging techniques may be particularly relevant for an optimal treatment.

The post 2011 – CLINAM Abstract – Thermosensitive Magnetoliposomes for MRI-Guided Drug Delivery – Meyr et al. first appeared on Nano Publications.]]>

Authors

Marie-Edith Meyre1, Cyril Lorenzato2, Matthieu Germain1, Pierre Smirnov2, Chrit Moonen2, Agnès Pottier1 and Laurent Levy1
1 – Nanobiotix, Paris, France
2 – Laboratoire Imagerie Moléculaire et Fonctionnelle. UMR 5231 CNRS / Université Bordeaux 2. France

Summary

Congress: CLINAM, 23rd May 2011

Contents: The development of new activatable drug nanocarriers, with multiple functionalities, presents a promising approach for cancer treatment.

Improved drug delivery and controlled drug release at the tumor site may have considerable benefit by increasing treatment efficacy while reducing side effects and toxicity. Further, the possibility to monitor both nanocarrier accumulation and drug release via current clinical imaging techniques may be particularly relevant for an optimal treatment.

Within the European project “Sonodrugs”, we investigated the opportunity of triggering the drug release from new nanocarriers (temperature and pressure-sensitive) thanks to High Intensity Focused Ultrasounds (HIFU) and monitoring the release profile of the drug at the tumor site thanks to Magnetic Resonance Imaging (MRI) imaging.

A new versatile thermosensitive liposome has been designed and developed to efficiently encapsulate a drug (doxorubicin) and a contrast agent (superparamagnetic iron oxide nanoparticles).

The post 2011 – CLINAM Abstract – Thermosensitive Magnetoliposomes for MRI-Guided Drug Delivery – Meyr et al. first appeared on Nano Publications.]]> https://bibliography.nanobiotix.com/fr/2011-clinam-abstract-thermosensitive-magnetoliposomes-for-mri-guided-drug-delivery-meyr-et-al/feed/ 0