Tomography | Nano Publications https://bibliography.nanobiotix.com/fr/ Navigate through all Nanobiotix publications online Tue, 24 May 2022 09:42:29 +0000 fr-FR hourly 1 https://wordpress.org/?v=6.0 https://bibliography.nanobiotix.com/wp-content/uploads/2019/11/cropped-n-icon-512x512-32x32.png Tomography | Nano Publications https://bibliography.nanobiotix.com/fr/ 32 32 2017 – AACR Abstract – NBTXR3 anti-tumor efficacy in vivo https://bibliography.nanobiotix.com/fr/2017-aacr-abstract-nbtxr3-anti-tumor-efficacy-in-vivo/ https://bibliography.nanobiotix.com/fr/2017-aacr-abstract-nbtxr3-anti-tumor-efficacy-in-vivo/#respond Wed, 01 Mar 2017 10:02:48 +0000 http://localhost:8888/bibliography/2017/03/01/2017-aacr-abstract-nbtxr3-anti-tumor-efficacy-in-vivo/ NBTXR3 has been evaluated in numerous in vivo models. The antitumor efficacy was systematically enhanced in terms of tumor growth delay for animals treated with NBTXR3 and exposed to radiotherapy when compared to radiotherapy alone. In this abstract the transferability of the treatment with NBTXR3 from one type of cancer to the other is described.

NBTXR3 is intended to be injected in the tumors. Spilling in the circulation may occur during product administration or, as expected, during tumor destruction, leading to steady trapping of NPs in the reticulo-endothelial system (liver and spleen). Clinically, it is unknown whether patients, previously treated with NPs, may show toxic signs when NPs are exposed (activation) to diagnosis imaging (computed tomography(CT)) of the liver.

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Authors

Ping Zhang, Sonia Vivet, Sébastien Paris, Agnès Pottier
Nanobiotix, Paris, France

Summary

NBTXR3 has been evaluated in numerous in vivo models. The antitumor efficacy was systematically enhanced in terms of tumor growth delay for animals treated with NBTXR3 and exposed to radiotherapy when compared to radiotherapy alone. In this abstract the transferability of the treatment with NBTXR3 from one type of cancer to the other is described.

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