{"id":1482,"date":"2018-06-21T18:07:33","date_gmt":"2018-06-21T17:07:33","guid":{"rendered":"http:\/\/bibliography.nanobiotix.com\/2018-estro-hafnium-oxide-nanoparticles-and-radiotherapy-a-promising-new-treatment-strategy\/"},"modified":"2022-05-24T16:51:31","modified_gmt":"2022-05-24T15:51:31","slug":"2018-estro-hafnium-oxide-nanoparticles-and-radiotherapy-a-promising-new-treatment-strategy","status":"publish","type":"post","link":"https:\/\/bibliography.nanobiotix.com\/fr\/2018-estro-hafnium-oxide-nanoparticles-and-radiotherapy-a-promising-new-treatment-strategy\/","title":{"rendered":"2018 \u2013 ESTRO \u2013 Hafnium Oxide Nanoparticles and Radiotherapy: A Promising New Treatment Strategy"},"content":{"rendered":"

[vc_row padding_top=\u00a0\u00bb0″ padding_bottom=\u00a0\u00bb0″ section_container_layout=\u00a0\u00bbfull-width\u00a0\u00bb remove_horizontal_padding=\u00a0\u00bbyes\u00a0\u00bb module_type=\u00a0\u00bbbg-color\u00a0\u00bb gutter_size=\u00a0\u00bbyes\u00a0\u00bb equal_height=\u00a0\u00bbyes\u00a0\u00bb bg_color=\u00a0\u00bb#28282e\u00a0\u00bb][vc_column][vc_row_inner padding_top=\u00a0\u00bb0″ padding_bottom=\u00a0\u00bb0″ gutter_size=\u00a0\u00bbyes\u00a0\u00bb equal_height=\u00a0\u00bbyes\u00a0\u00bb][vc_column_inner column_paddings=\u00a0\u00bb105″ column_position_vertical=\u00a0\u00bbmiddle\u00a0\u00bb column_min_height=\u00a0\u00bb700″ column_min_height_sm=\u00a0\u00bb400″ column_min_height_xs=\u00a0\u00bb350″ module_type=\u00a0\u00bbbg-image\u00a0\u00bb bg_image=\u00a0\u00bb102″ mask_fx=\u00a0\u00bbyes-mask\u00a0\u00bb mask_color_mode=\u00a0\u00bbpalette\u00a0\u00bb mask_bg_color_palette=\u00a0\u00bbmain-mask\u00a0\u00bb animation_fx=\u00a0\u00bbyes-animation\u00a0\u00bb animation_delay=\u00a0\u00bb200″ animation_offset_scroll_down=\u00a0\u00bb90″ width=\u00a0\u00bb1\/2″ animation_in=\u00a0\u00bbfadeInUp\u00a0\u00bb][vc_empty_space height=\u00a0\u00bb60px\u00a0\u00bb responsive_lg=\u00a0\u00bbhidden\u00a0\u00bb responsive_md=\u00a0\u00bbhidden\u00a0\u00bb][az_box_icons box_icon_title=\u00a0\u00bbAuthors\u00a0\u00bb box_icon_color_mode=\u00a0\u00bbon-the-fly\u00a0\u00bb icon_visibility=\u00a0\u00bbyes-icon\u00a0\u00bb icon_type=\u00a0\u00bbfont\u00a0\u00bb icon=\u00a0\u00bbfa fa-edit\u00a0\u00bb icon_color_mode=\u00a0\u00bbon-the-fly\u00a0\u00bb icon_size=\u00a0\u00bb50″ box_icon_color=\u00a0\u00bb#ffffff\u00a0\u00bb icon_color=\u00a0\u00bb#ffffff\u00a0\u00bb]Le Tourneau C.1<\/span>, Le Pechoux C.2<\/span>, Kantor G.3<\/span>, Carrere S.4<\/span>, Bonvalot S.1<\/span>, Le Prise E.5<\/span>, Nguyen F.2<\/span>, Baumann A. S.6<\/span>, Vendrely V.7<\/span>, Bronowicki J. P.8<\/span>, Moreno-Garcia V.9<\/span>, Delannes M.10<\/span>, Thariat J.11<\/span>, Papai Z.12<\/span>, Ruthowski P.13<\/span>, Tiangco B.14<\/span>, Rastrelli M.15<\/span>, Agoston P.16<\/span>, Sunyach M.P.17<\/span>, Rubi Li K.18<\/span>, Mervoyer A.19<\/span>, Sy-Ortin T.20<\/span>, Hong A.21<\/span>, Anghel R.22<\/span>, Gronchi A.23<\/span>
\n1 \u2013 Institut Curie, Oncology, Paris, France
\n2 \u2013 Institut Gustave Roussy, Oncology, Villejuif, France
\n3 \u2013 Institut Bergoni\u00e9, Oncology, Bordeaux, France
\n4 \u2013 ICM, Oncology, Montpellier, France
\n5 \u2013 Eug\u00e8ne Marquis, Oncology, Rennes, France
\n6 \u2013 Canc\u00e9rologie de Lorraine, Oncology, Nancy, France
\n7 \u2013 H\u00f4pital du Haut-L\u00e9v\u00eaque, Oncology, Bordeaux, France
\n8 \u2013 H\u00f4pitaux de Brabois CHU Nancy, Oncology, Nancy, France
\n9 \u2013 START Madrid, Oncology, Madrid, Spain
\n10 \u2013 Claudius Regaud, Oncology, Toulouse, France
\n11 \u2013 Antoine Lacassagne, Oncology, Nice, France
\n12 \u2013 Medical Centre- Hungarian Defence Forces, Oncology, Budapest, Hungary
\n13 \u2013 Maria Sklodowska-Curie Institute – Oncology Center, Warsaw, Poland
\n14 \u2013 The Medical City, Oncology, Pasig City, Philippines
\n15 \u2013 Veneto institute of oncology, Padua Italy
\n16 \u2013 Orsz\u00e1gos Onkol\u00f3giai Int\u00e9zet, Oncology, Budapest, Hungary
\n17 \u2013 Centre L\u00e9on B\u00e9rard, Oncology, Lyon, France
\n18 \u2013 St. Luke\u2019s Medical Center, Oncology, Quezon City, Philippines
\n19 \u2013 Centre Rene Gauducheau- CLCC Nantes Atlantique, Oncology, St Herblain, France
\n20 \u2013 University of Santo Thomas, Oncology, Manila, Philippines
\n21 \u2013 Chris O\u2019Brien Lifehouse, Oncology, Sidney, Australia
\n22 \u2013 Institutul Oncologic Bucuresti- \u201cProf. Dr. Alexandru Trestioreanu\u201d, Oncology, Bucharest, Romania
\n23 \u2013 Fondazione IRCCS Istituto Nazionale dei Tumori, Oncology, Milan, Italy<\/span>[\/az_box_icons][vc_empty_space height=\u00a0\u00bb60px\u00a0\u00bb responsive_lg=\u00a0\u00bbhidden\u00a0\u00bb responsive_md=\u00a0\u00bbhidden\u00a0\u00bb][\/vc_column_inner][vc_column_inner column_paddings=\u00a0\u00bb105″ column_position_vertical=\u00a0\u00bbmiddle\u00a0\u00bb module_type=\u00a0\u00bbbg-color\u00a0\u00bb animation_fx=\u00a0\u00bbyes-animation\u00a0\u00bb animation_delay=\u00a0\u00bb300″ animation_offset_scroll_down=\u00a0\u00bb90″ width=\u00a0\u00bb1\/2″ bg_color=\u00a0\u00bb#ffffff\u00a0\u00bb animation_in=\u00a0\u00bbfadeInUp\u00a0\u00bb][vc_empty_space height=\u00a0\u00bb60px\u00a0\u00bb responsive_lg=\u00a0\u00bbhidden\u00a0\u00bb responsive_md=\u00a0\u00bbhidden\u00a0\u00bb][az_box_icons box_icon_title=\u00a0\u00bbSummary\u00a0\u00bb icon_visibility=\u00a0\u00bbyes-icon\u00a0\u00bb icon_type=\u00a0\u00bbfont\u00a0\u00bb icon=\u00a0\u00bbaz-icon az-icon-layers2″ icon_color_mode=\u00a0\u00bbon-the-fly\u00a0\u00bb icon_color=\u00a0\u00bb#28282e\u00a0\u00bb icon_size=\u00a0\u00bb50″]With recent advances in radiation delivery techniques, an increasing number of cancer patients undergo radiotherapy. However, due to the non-targeted nature of radiotherapy, doses are limited by potential toxicity to surrounding normal tissue. Thus, a major challenge remains to develop new strategies to improve the tumor selectivity of radiation therapy. Nanobiotix has developed NBTXR3 – a hafnium oxide nanoparticle that can enter tumor cells and deposit high levels of energy in cells when exposed to ionizing radiation thereby increasing tumor-specific physical killing through DNA damage\/cell destruction and enhancing the intratumoral immune profile.<\/p>\n

At 2018 ESTRO<\/em>, an overview of NBTXR3 was presented, describing its role in current 7 clinical trials.[\/az_box_icons][vc_empty_space height=\u00a0\u00bb60px\u00a0\u00bb responsive_lg=\u00a0\u00bbhidden\u00a0\u00bb responsive_md=\u00a0\u00bbhidden\u00a0\u00bb][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row]<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"

With recent advances in radiation delivery techniques, an increasing number of cancer patients undergo radiotherapy. However, due to the non-targeted nature of radiotherapy, doses are limited by potential toxicity to surrounding normal tissue. Thus, a major challenge remains to develop new strategies to improve the tumor selectivity of radiation therapy. [\u2026]<\/p>\n","protected":false},"author":1,"featured_media":1479,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[182,183,669,673,674,668],"tags":[481,482,196,465,475,461,342,200,483],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/bibliography.nanobiotix.com\/fr\/wp-json\/wp\/v2\/posts\/1482"}],"collection":[{"href":"https:\/\/bibliography.nanobiotix.com\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bibliography.nanobiotix.com\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bibliography.nanobiotix.com\/fr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/bibliography.nanobiotix.com\/fr\/wp-json\/wp\/v2\/comments?post=1482"}],"version-history":[{"count":1,"href":"https:\/\/bibliography.nanobiotix.com\/fr\/wp-json\/wp\/v2\/posts\/1482\/revisions"}],"predecessor-version":[{"id":2433,"href":"https:\/\/bibliography.nanobiotix.com\/fr\/wp-json\/wp\/v2\/posts\/1482\/revisions\/2433"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bibliography.nanobiotix.com\/fr\/wp-json\/wp\/v2\/media\/1479"}],"wp:attachment":[{"href":"https:\/\/bibliography.nanobiotix.com\/fr\/wp-json\/wp\/v2\/media?parent=1482"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bibliography.nanobiotix.com\/fr\/wp-json\/wp\/v2\/categories?post=1482"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bibliography.nanobiotix.com\/fr\/wp-json\/wp\/v2\/tags?post=1482"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}