SBRT | Nano Publications

2018-ASTRO 2018- NBTXR3 in liver cancers

Clinical Data NBTXR3, Congress Abstracts, Liver

Radiation oncology technological development is principally focused in improving the precision of radiotherapy (RT) and reducing unwanted irradiation to normal tissues. There is an unmet medical need into ameliorating the energy dose deposit within tumor cells without increasing the dose received by surrounding healthy tissues. […]

2018 – ESMO – NBTXR3 in HCC and Liver Metastasis

Clinical Data NBTXR3, Congress Abstracts, Head & Neck, Liver

For patients (pts) with hepatocellular carcinoma (HCC) or liver metastasis (liver mets), stereotactic body radiation therapy (SBRT) is a well-tolerated option. Yet, the risk of injury to normal tissues limits the ability to efficiently sterilize tumor cells. Thus, hafnium oxide nanoparticles, NBXTR3, were developed, which increase the interaction of radiotherapy energy dose deposition within tumor cells when activated by an ionizing energy source like SBRT. […]

2018 – ESMO WGI – NBTXR3 in HCC and Liver Mets

Clinical Data NBTXR3, Congress Abstracts, Liver

Management of hepatocellular carcinoma (HCC) and liver metastasis (mets) requires complementary expertise of multiple specialties. Treatment decisions are increasingly complex and physicians must face a wide range of underlying liver dysfunctions and concomitant malignancies. Among available treatments, stereotactic body radiation therapy (SBRT) is well-tolerated. […]

2018 – ASCO – NBTXR3 in the treatment of liver cancer: a phase I/II trial

Clinical Data NBTXR3, Congress Abstracts, Liver

With recent advances in radiation delivery techniques, an increasing number of cancer patients undergo radiotherapy. However, due to the non-targeted nature of radiotherapy, doses are limited by potential toxicity to surrounding normal tissue. Thus, a major challenge remains to develop new strategies to improve the tumor selectivity of radiation therapy. […]

2018 – ESTRO – Hafnium Oxide Nanoparticles and Radiotherapy: A Promising New Treatment Strategy

Clinical Data NBTXR3, Congress Abstracts, Head & Neck, Liver, Rectum, STS